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Can I Take CBD Oil With Citalopram

Many people who are considering using CBD oil may wonder if it is safe to take alongside their current medication, such as citalopram. Citalopram is a commonly prescribed medication for depression and anxiety disorders, and it belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs).

Before we delve into this topic, it’s important to note that we are not medical professionals, and this information should not replace advice from your healthcare provider. However, we can provide some insights based on existing research and anecdotal evidence.

Understanding CBD Oil and Citalopram

CBD, or cannabidiol, is a natural compound derived from the cannabis plant. It has gained popularity due to its potential therapeutic benefits, such as reducing anxiety, promoting relaxation, and relieving pain. CBD works by interacting with the body’s endocannabinoid system, which plays a role in regulating various physiological processes.

Citalopram, on the other hand, is an SSRI that works by increasing the levels of serotonin in the brain. Serotonin is a neurotransmitter that helps regulate mood, emotions, and sleep. By preventing the reabsorption of serotonin, citalopram helps improve mood and reduce symptoms of depression and anxiety.

Potential Interactions

While CBD and citalopram have different mechanisms of action, there is a possibility of interactions between the two substances. Both CBD and citalopram are metabolized by enzymes in the liver, specifically the cytochrome P450 (CYP450) enzymes. These enzymes are responsible for breaking down medications and toxins in the body.

Some studies suggest that CBD may inhibit the activity of certain CYP450 enzymes, including CYP2D6 and CYP3A4, which are involved in metabolizing citalopram. This could potentially lead to increased levels of citalopram in the bloodstream, which may cause adverse effects or alter its efficacy.

Consulting with Your Healthcare Provider

If you are considering taking CBD oil alongside citalopram, it is crucial to consult with your healthcare provider. They can provide personalized advice based on your specific situation and medical history. Your healthcare provider may consider factors such as the dosage of citalopram, your overall health, and any other medications you may be taking.

It’s important to note that CBD can also interact with other medications, not just citalopram. Therefore, it is always recommended to inform your healthcare provider about any supplements or alternative therapies you are considering.


While CBD oil may hold promise as a natural remedy for various conditions, including anxiety and depression, it is essential to approach its use cautiously, especially when taking other medications like citalopram. The potential for interactions between CBD and citalopram highlights the importance of consulting with healthcare professionals before making any changes to your treatment plan.

Remember, your healthcare provider is the best resource to provide guidance and ensure your safety and well-being. They can help you make informed decisions about incorporating CBD oil into your existing medication regimen, taking into account potential risks and benefits.

At Canavape, we prioritize the health and well-being of our customers. We encourage you to seek professional medical advice and make informed choices regarding your health. If you have any questions or concerns about CBD oil and its potential interactions with citalopram or any other medication, please consult with your healthcare provider before trying CBD oil as part of your wellness routine.

The information provided in this article is for educational purposes only & is not intended to promote any specific products. None of our products are designed for the treatment, prevention, or cure of any disease. This content should not be considered as professional or medical advice. For specific concerns, consult a qualified expert.

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